Up to three times the dose: stoners need more anesthetic

Who consumed Cannabis regularly, during surgery a higher need for General Anesthesia. In the case of Propofol, for example, may be more than three times the dose needed, when people take on a daily or weekly marijuana or other hemp products. The report by researchers Mark Twardowski of the Western Medical Associates in Grand Junction (Colorado, USA) in the professional magazine “The Journal of the American Osteopathic Association”. “Cannabis has some metabolic effects which we do not understand, and the patients need to know that your cannabis consumption of other drugs may be less effective,” says Twardowski.

Surprisingly, the result is not the case, says Götz Geldner, Medical Director of the clinic for anesthesiology, intensive care medicine, emergency medicine and pain therapy, Klinikum Ludwigsburg. Patients who take psychoactive substances such as alcohol, need more anesthetic, is anesthesiologists have long known, says the study involved physicians. In one of the German society for anaesthesiology and intensive care medicine recommended patient questionnaire you will be asked for about ten years after the drug use. After Geldners evaluation more than 90 percent of the German hospitals using a comparable questionnaire.

Liver metabolized anesthetics faster

Geldner points out that accurate results are obtained only with the measure of substances from the cannabis plant in the blood. “When the liver gets often to do with cannabinoids or alcohol, it increases its detoxifying function,” he explains. Subsequently, an anesthetic would be metabolized faster. In addition to drugs and alcohol and even tranquilizers and other psychotropic drugs therefore affect the effectiveness of anesthetics.

Since 2012, the US-Federal state of Colorado, drug types of the hemp plant (Cannabis) is legal consumed. Also in nine other States, the taking is allowed. These legal Changes have led to the consumption of cannabis products in the USA has increased from 2007 to 2015 to 43 percent. Estimated almost 14 percent of adults in this period hemp drugs to themselves.

Twardowski leads to a hospital in Grand Junction the intestines and Stomach reflection. The researchers selected from 1158 to his patients in the years 2016 and 2017, according to the random principle, 250, of which 25 regular cannabis use had given. It is a balance of the medical procedure used in amounts of anesthetic agents with the information to the patient about the ingestion of cannabis products, alcohol, benzodiazepines (e.g. psychoactive drugs), and opiates. Users of hemp drugs is required, therefore, in the middle 14 percent more Fentanyl, nearly 20 percent more Midazolam and 220 percent more Propofol – namely, 44,81 milligrams instead of 13,83 milligrams.