Melanoma thickness equally hard for algorithms and dermatologists to judge

Assessing the thickness of melanoma is difficult, whether done by an experienced dermatologist or a well-trained machine-learning algorithm. A study from the University of Gothenburg shows that the algorithm and the dermatologists had an equal success rate in interpreting dermoscopic images.

In diagnosing melanoma, dermatologists evaluate whether it is an aggressive form (“invasive melanoma”), where the cancer cells grow down into the dermis and there is a risk of spreading to other parts of the body, or a milder form (“melanoma in situ,” MIS) that develops in the outer skin layer, the epidermis, only. Invasive melanomas that grow deeper than one millimeter into the skin are considered thick and, as such, more aggressive.

Importance of thickness

Melanomas are assessed by investigation with a dermatoscope — a type of magnifying glass fitted with a bright light. Diagnosing melanoma is often relatively simple, but estimating its thickness is a much greater challenge.

“As well as providing valuable prognostic information, the thickness may affect the choice of surgical margins for the first operation and how promptly it needs to be performed,” says Sam Polesie, associate professor (docent) of dermatology and venereology at Sahlgrenska Academy, University of Gothenburg, Polesie is also a dermatologist at Sahlgrenska University Hospital and the study’s first author.

Tie between man and machine

Using a web platform, 438 international dermatologists assessed nearly 1,500 melanoma images captured with a dermatoscope. The dermatologists’ results were then compared with those from a machine-learning algorithm trained in classifying melanoma depth.

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