Alzheimer’s could be diagnosed decades early: Docs find dementia sleep clue

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They found the hippocampus, an area controlling memory, did not wind down as it should in sleeping mice with early signs of the dementia disease. The overactivity – likened to an electrical pattern seen in people with epilepsy – was also evident under a general anaesthetic.

The findings pave the way to early checks for Alzheimer’s using skull caps fitted with electrodes – EEGs. And the Tel Aviv University doctors suggest they could also be incorporated when a patient has an operation.

Spotting the signs early would mean more effective treatment before it is too late. One option may be a drug used for multiple sclerosis – which successfully quelled the night-time brain activity in the mice.The research appears in Cell Reports.

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